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The process of clonal selection is a fundamental principle of adaptive immunity. It involves the activation and expansion of specific B and T cells in response to an antigen.

Clonal selection begins when an antigen enters the body, either through infection or vaccination. Antigens are proteins or other molecules that can trigger an immune response.

When an antigen is encountered, specialized cells of the immune system called antigen-presenting cells (APCs) capture and process it. They then present small fragments of the antigen, called epitopes, on their cell surface using a protein called major histocompatibility complex (MHC).

Next, naive B and T cells, which have not encountered the specific antigen before, circulate through the body and can recognize the presented epitopes. When a B or T cell recognizes an epitope that matches its specific receptor, it becomes activated.

Once activated, the B or T cell begins to divide and proliferate, creating a large number of identical copies, or clones. This is called clonal expansion. Clonal expansion allows for a stronger and more specific immune response.

During clonal expansion, B cells differentiate into plasma cells, 네이버 아이디 구매 which produce and secrete large amounts of antibodies specific to the antigen. Antibodies help neutralize the antigen and mark it for destruction by other components of the immune system.

T cells, on the other hand, can differentiate into various types of effector cells, such as cytotoxic T cells or helper T cells. Cytotoxic T cells directly kill infected cells, while helper T cells coordinate and enhance the immune response.

After the infection or vaccination has been cleared, most of the effector cells undergo programmed cell death, 네이버 실명 아이디 판매 known as apoptosis. However, a small population of activated B and T cells survive as memory cells. These memory cells provide long-term immunity and can mount a faster and more robust response if the same antigen is encountered again in the future.

Overall, clonal selection is a crucial mechanism in adaptive immunity, allowing the immune system to specifically target and eliminate pathogens.

이 게시를 좋아하고 네이버 실명 아이디 구매 인터넷 사이트를 방문하여 더 많은 정보를 얻고 싶다면 네이버 아이디 판매.